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Bipolar medication should treat bipolar symptoms

All of my research and experience has convinced me that the primary goal of bipolar medication MUST be mood stabilization.

Although some other medication treatments are available and come in and out of fashion, in this section our major focus will be on mood stabilizing bipolar drugs as the first line treatment for bipolar symptoms.

Obviously the primary goal of taking medication is to treat bipolar symptoms, first and foremost.

When a person has manic-depressive illness, there are 4 main things they need from their bipolar medication:

1. Episode Prevention: You need to avoid both manic and depressive episodes. Remember, each episode you have increases the likelihood of further episodes - and failure to medicate is major cause of relapse (the return of serious bipolar symptoms).

2. Mood Control: Bipolar is a mood disorder so mood control is the primary goal. This is why the mood stabilizers are your best bet for effective bipolar medication - they treat both mania AND depression - (i.e. both of the both bipolar symptoms - as well as protecting you from future episodes.

3. Neural Protection: It has been shown that each extreme mood episode can cause damage to the brain. However, some medications actually help protect the brain from damage.

4. Treatment for an Acute Phase: If you are already in the grip of pronounced mania or depression and are exhibiting severe bipolar symptoms, you need to return to a balanced mood ASAP.

Best drugs for bipolar symptoms

Today there are many bipolar drugs in use. Detailed information on the top 15 can be found by clicking the links at the VERY BOTTOM of this webpage.

Also, this is an area where you should seek expert advice from a specialist who has lots of bipolar experience.

However, there are clear treatment guidelines and there is a definite gold standard approach that emphasizes trying the proven mood stabilizers first.

Lamictal is a very important new bipolar medication.
It is therefore possible to suggest that these mood stabilizers are the bipolar medications to try first. If your doctor does not suggest one of these (maybe in combination with something else), you should ask for some more information.

1. Lithium

2. Lamictal (lamotrigine)

3. Depakote (sodium valproate).

Learn about medication for bipolar depression

Bipolar disorder drugs to avoid

Mood stabilizers are the bipolar medication most likely to help you.
For people with bipolar disorder, it is more typical to suffer from bipolar symptoms of depression than mania.

Although the fallout from manic episodes can be particularly destructive, and it is occurrence of mania that characterizes bipolar disorder, most bipolar people will spend more time being struggling with their bipolar symptoms of depression rather than mania.

Also, research shows that bipolar depression is harder to treat than bipolar mania. And - as many of us found out the hard way - it is still common for medical professionals to misdiagnose bipolar disorder as depression.

For these reasons, many bipolar people are given antidepressant drugs. DON'T TAKE THEM UNLESS YOU ALSO TAKE A MOOD STABILIZER AND/OR HAVE HAVE A DETAILED JUSTIFICATION FROM YOUR PSYCHIATRIST! The latest research suggests that antidepressants are either pointless or downright dangerous if what you really have is manic-depressive illness.

There is no good evidence that continuous use of an antidepressant prevents further episodes of bipolar depression. EVEN WORSE - there is a definite risk of them causing a switch to mania.

In particular, SSRI drugs are NOT effective bipolar medications. However, "Benzo" antidepressants such as Klonopin, Xanax, Valium, or Ativan may be very helpful for anxiety and panic.

A controversial bipolar medication that must be carefully discussed with your doctor.
Also, steer away from atypical anti-psychotics until you have tried the mood stabilizers and anti-convulsant drugs (see bottom of page). An exception is Seroquel (quetiapine), which has a great track record, although some people do gain weight on it. Zyprexa (olanzapine) is to avoided - it can lead to substantial weight gain and diabetes.

Although these drugs have recently been fashionable bipolar medications and do have some research to support their effectiveness, there is a lot of debate about the conduct of the drug companies and the doctors they paid to conduct these studies. Also, in some US states there have been lawsuits and legal settlements. There is evidence that these drugs have been pushed in inappropriate ways, and have severe side effects that consumers are not suitably warned about. Zyprexa is the biggest culprit.

Abilify is popular because some believe it does not have these same weight gain problems (although it does) and there is an now evidence to support its effectiveness for treating both mixed episodes and bipolar mania.

Does Abilify cause weight gain?

Wikipedia article on bipolar drugs

Bipolar meds tips

We discuss lithium side effects, toxicity symptoms, and compliance tips in lots of detail elsewhere on the Bipolar Lives website, so we won't deal with lithium in any more detail here.
Some sources cite Depakote as the most frequently prescribed bipolar medication.


1. Depakote (Valproate)

This is one of the most tried and tested bipolar meds and is an excellent mood stabilizer to consider, especially for men. Like all drugs, there can be an adjustment period, with side effects such as nausea and indigestion, sleepiness, and hand tremors. To cope with these while you settle in, we suggest you ask for the slow release version and take your tablets after food. If they make you feel sleepy, then try taking your dose at night. Taking your meds with food and cutting down on caffeine will help with hand tremors (although most people don't have this side effect). Teenage girls should NOT use Depakote as it may cause PCOS in girls under 20.

2. Lamictal (Lamotrigine)

Fast emerging as a favored treatment, Lamictal is very useful for the treatment and prevention of bipolar depression and rapid-cycling. However, some studies suggest Lamictal may be less effective for mania. It is often used in combination with another bipolar drug. The most dangerous side effect is a rash, which can be fatal, so watch for it and tell your doctor immediately (don't panic - it is rare).

Bipolar medication table


What Other Visitors Have Said

Click below to see bipolar medication ratings and reviews from other visitors to this page...

Topamax (Topiramte) for Bipolar: Florida settles with maker of Topamax  starstarstarstarstar
The maker of Topamax (an anti-convulsant medication drug used to treat epilepsy) will pay Florida $3 million to settle allegations it marketed the drug ...

Wellbutrin / Zyban for Bipolar (Bupropion)  starstarstarstarstar
US BRAND NAME: Wellbutrin

GENERIC NAME: Bupropion

TYPE: Atypical antidepressant

USE: An antidepressant that is also effective in helping people ...

Lamictal for Bipolar (Lamotrigine)  starstarstarstarstar
US BRAND NAME: Lamictal

GENERIC NAME: Lamotrigine

TYPE: Anticonvulsant and Mood Stabilizer

USE: Treatment of bipolar depression. Its main use ...

Klonopin for Bipolar (Clonazepam)  starstarstarstarstar
US BRAND NAME: Klonopin

GENERIC NAME: Clonazepam

TYPE: Benzodiazepine

USE: Klonopin is used to treat certain seizure disorders. It is also used ...

Zyprexa for Bipolar (Olanzapine)  starstarstarstarstar
US BRAND NAME: Zyprexa

GENERIC NAME: Olanzapine

TYPE: Atypical antipsychotic

USE: Zyprexa is another of the atypical antipsychotics that dampen ...

Tegretol for Bipolar (Carbamazepine)  starstarstarstarstar
US BRAND NAME: Tegretol

GENERIC NAME: Carbamazepine

TYPE: Anticonvulsant

USE: Tegretol is used to control seizures in the treatment of epilepsy,...

Seroquel for Bipolar (Quetiapine)  starstarstarstarstar
US BRAND NAME: Seroquel

GENERIC NAME: Quetiapine

TYPE: Atypical antipsychotic

USE: Can reduce symptoms of mania, such as feeling upset, racing ...

Depakote for Bipolar (Valproate)  starstarstarstarstar
US BRAND NAME: Depakote

GENERIC NAME: Valproate

TYPE: Anticonvulsant and mood stabilizer.

USE: Used to control seizures in the treatment of epilepsy....

Trileptal for Bipolar (Oxcarbazepine)  starstarstarstar
US BRAND NAME: Trileptal

GENERIC NAME: Oxcarbazepine

TYPE: Anticonvulsant

USE: Another anticonvulsant originaly developed to treat epilepsy, Trilepal ...

Lithium for Bipolar (Brand names include Eskalith, Lithobid)  starstarstarstar
US BRAND NAME: Eskalith, Lithobid

GENERIC NAME: Lithium

TYPE: Mood Stabilizer

USE: Lithium is used to treat mania that is part of bipolar disorder ...

Abilify for Bipolar (Aripiprazole)  starstarstarstar
US BRAND NAME: Abilify

GENERIC NAME: Aripiprazole

TYPE: Atypical or "2nd generation" anti-psychotic.

USE: Treatment of schizophrenia, unipolar ...

Saphris for Bipolar (Asenapine)  starstarstarstar
US BRAND NAME: Saphris

GENERIC NAME: Asenapine

TYPE: Atypical antipsychotic

USE: helps people with Bipolar I manage the symptoms of manic or mixed ...

Risperdal for Bipolar (Risperidone)  starstarstarstar
US BRAND NAME: Risperdal

GENERIC NAME: Risperidone

TYPE: Atypical antipsychotic

USE: Risperdal is used to treat the symptoms of psychotic disorders,...

Neurontin for Bipolar (Gabapentin)  starstarstarstar
US BRAND NAME: Neurontin

GENERIC NAME: Gabapentin

TYPE: Anticonvulsant

USE: Main use is to prevent epileptic seizures. It increases the amount ...

Geodon for Bipolar (Ziprasidone)  starstarstar
US BRAND NAME: Geodon

GENERIC NAME: Ziprasidone

TYPE: Atypical antipsychotic.

USE: Used to treat symptoms of mental or psychotic disorders, such ...

Symbyax for Bipolar (Zyprexa and Prozac combination)  starstar
US BRAND NAME: Symbyax

GENERIC NAME: Olanzapine and Fluoxetine Hydrochloride

TYPE: Atypical antipsychotic combined with SSRI antidepressant

USE:...

Abilify  star
I was at a starting weight of 120 lbs. I was on Abilify for approximately 3 months and by the end of the 3 months i weighed 145. I did not eat differently ...


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